2016年6月25日星期六

How to distinguish between acute and chronic glomerulonephritis

glomerulonephritis
This article review: divided into acute and chronic glomerulonephritis, how to distinguish the difference between the two? Together, the difference between acute glomerulonephritis and chronic glomerulonephritis.

The difference between acute and chronic glomerulonephritis! Most patients with chronic nephritis etiology is not clear, the clinical characteristics of the disease for a long time, can be a period of asymptomatic period, showed a slow progressive disease.

How to distinguish between acute and chronic glomerulonephritis and how to distinguish between acute and chronic glomerulonephritis

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Acute glomerulonephritis

Clinical manifestations of acute onset, hematuria, proteinuria, edema, hypertension and glomerular filtration rate decreased as the characteristics of the glomerular disease, it is also often referred to as acute nephritis syndrome. The vast majority of patients with acute infection of the glomerular nephritis.

Chronic glomerulonephritis

Referred to as chronic nephritis, proteinuria, hematuria, hypertension, edema as the basic clinical manifestations, mode of onset is different, protracted illness, the slow progress of pathological changes can be varying degrees of renal function decline, will eventually develop chronic renal failure of a group of glomerular disease. Because of the different pathological types and stages of the disease, the main clinical manifestations of the disease are different.

What is the difference between acute and chronic glomerulonephritis?

Urine routine examination, to see the red cells in the different degree of proteinuria, microscopic examination, most patients have varying degrees of hypertension and impaired renal function. The clinical manifestations of chronic nephritis were similar, but the pathological types and the severity of the lesions were different. According to the major lesions of the majority of the glomerular lesions, divided into mesangial proliferative glomerulonephritis, membranous nephropathy, focal segmental glomerular sclerosis, mesangial capillary glomerulonephritis, proliferative glomerulonephritis.

Acute poststreptococcal glomerulonephritis protracted course, can turn into chronic nephritis in 1 years. But most chronic nephritis is not by the persistent acute nephritis, generally due to the immune mechanism of long-term effects and long-term renal hemodynamic changes and renal vascular changes, changes in membrane function caused by.

Previously is generally believed that acute glomerular nephritis if proteinuria and microscopic hematuria sustained for more than 6 months to 1 year that has been transferred to chronic, in recent years renal biopsy and clinical data found that urinary abnormalities after acute nephritis and renal biopsy tissue activity of 2 ~ 3 years follow-up in gradually disappear. Therefore, it should not be judged by time alone to distinguish between acute or chronic glomerulonephritis.

According to the follow-up data and vanishes when the clinical manifestations of acute glomerular nephritis kidney still have residual disease, but sometimes a glomerular fibrosis, sometimes in urine routine examination still found protein and red blood cells, biopsy found kidney diffuse inflammatory lesions disappeared and only focal lesions residues, the so-called "defect healing". Some patients were followed up for a long time, and there was an increase in the number of glomerular fibrosis in the biopsy. In case of the above should continue to follow-up, there is no possibility of attention to develop chronic glomerulonephritis.

Chronic nephritis patients with acute seizure predisposition, each in the disease at a relatively stable situation, due to respiratory tract infection or other sudden malignant stimulation, in the short term (3 ~ 5 days even 1 ~ 2 days) disease abrupt deterioration when patients large proteinuria, even to the naked eye hematuria, tube type increased. Obvious edema and hypertension, and deterioration of renal function. After appropriate treatment, the disease can be alleviated, basically restored to the original level, but also may lead to disease progression, into the uremia period.


MAORE INFOERMATION:http://www.kidneytherapychina.org/kidney-disease/

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