Renal biopsy puncture called, simply, is to remove the part of the kidney tissue with the instrument, obtained by the Department of Pathology, pathology reports, so that you can determine the pathological type of kidney disease.
So, the biggest role is to determine renal biopsy pathology, facilitates doctor treatment plan.
What are the benefits of renal biopsy?
We usually call "nephrotic syndrome", "chronic nephritis", etc., are very general concept, the specific histological type, you need to renal biopsy to determine.
Such as nephrotic syndrome, it's just a series of clinical symptoms, collectively, many pathological types can be manifested as nephrotic syndrome, such as some primary renal disease: minimal change nephropathy, membranous nephropathy, mesangial proliferative glomerulonephritis, bureau stove segmental glomerular sclerosis, as well as some secondary nephropathy: systemic lupus erythematosus nephritis, diabetic nephropathy, hypertensive nephropathy, and so on.
These pathological type of determination of the treatment plan is very important. Imagine, a membranous nephropathy patients and a minimal change nephropathy patients, although both nephrotic syndrome, but the focus of treatment is certainly not the same, if the same drugs are used, what the consequences will arise?
What are the drawbacks of renal biopsy?
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The biggest drawbacks is the secondary damage to the kidneys, and infection troubles.
She had kidney disease, kidney damage already, while renal biopsy surgery, will cause further damage to the kidneys. More importantly, whenever surgery, there will be the risk of infection, and kidney patients fear most is infection.
In addition, renal biopsy accuracy is not so high. Millions of kidney nephron, puncture can only remove a small part, a small part of this can not accurately reflect the situation of the entire kidney, there is no guarantee.
In addition to renal biopsy, we can not determine the pathological type?
General hospital Nephrology generally not the key departments, so research forces are relatively weak, but in some kidney specialist hospitals, in terms of pathology tests have a clear advantage.
Imported from Germany Roche COBAS8000 immune biochemical pattern analysis system, only one blood, you can complete biochemical (such as liver function, kidney function, cardiovascular screening, immune function, cardiac function enzymes, electrolytes) and immunological tests (thyroid function, tumor markers, hormones, infectious diseases, cardiac, etc.).
Siemens BN II specific protein analyzer, through the patient's urine, analysis and species composition in which urine protein, so they know the location and extent of kidney damage in patients. Early screening and efficacy evaluation for kidney disease, the distinction between glomerular injury or tubular injury
UF500i-AX4030 urine analysis pipeline Gao Olympus ultra-magnification microscope, a common component of urine physical component analysis system. Using semiconductor laser flow cytometry and specific for nucleic acid fluorescent dye staining technique for quantitative detection of urinary sediments, and can make homogeneity and heterogeneity analysis of red blood cells in urine, to determine renal hematuria is important.
Urine ultra-high-power microscope examination is the gold standard, but because of time-consuming, many hospitals did not use, so 10 minutes can be a urine test results, and we need 30 minutes.
Abbott ARCHITECT® i1000SR automated immunoassay analyzer, its biggest role is to monitor the plasma concentration, and plasma concentration, is a necessary means to cause different individuals to choose the best treatment options and the most appropriate treatment dose clinically.
Determine the pathological type of kidney disease treatment is significant, but through the blood, and urine can be determined pathological type, necessity renal biopsy on low.
