2015年10月11日星期日

What Are The Complications of Uremia

Effect of uremic state of metabolism

Carbohydrate metabolism disorders

Uremic patients mildly elevated blood sugar, which increased with different mechanisms of diabetes, diabetes is absolute or relative insulin secretion, and hyperglycemia uremic patients mainly cells to insulin sensitivity decreased. A certain amount of normal oral glucose, serum insulin increased accordingly; if it is diabetes, which increased more significantly, suggesting the need for more insulin than normal cells use glucose. According to reports, uremic patients within the normal endogenous insulin secretion, ingestion of exogenous insulin levels in the body to maintain higher than normal, due to the insulin in the blood of uremic patients can be maintained for a longer period of time, chronic diabetes, once After uremia, insulin dosage can be reduced.

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Protein metabolism

Protein metabolism of nitrogenous waste, since not ranked in vitro, in vivo accumulation, blood urea nitrogen increased. Therefore, in the treatment of uremia, generally limit the intake of protein, malnourished patients, patients undergoing long-term hemodialysis, protein intake can be slightly relaxed some restrictions, uremia abnormal levels of serum amino acids, some people Serum concentrations of certain amino acids can be 2 to 3 times higher than normal. On the other hand, serum essential amino acid content may be lower than normal people, the lack of essential amino acids, for autologous tissue reconstruction may be greatly affected.

Fat metabolism


Effect of uremia on fat metabolism has not been much research, it is known most dialysis patients, increased serum triglycerides and free fatty acid levels, blood cholesterol and phospholipids normal.

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