of the patients showed for the naked eye or microscope, 35% ~ 40% of patients performance for microscopic hematuria accompanied by,
the rest of the performance of nephropathy integrated syndrome and renal failure. The vast majority of patients will appear edema
phenomenon. So, why IgA nephropathy patients with edema, the following to listen to the experts to introduce.
Why there is edema in IgA nephropathy patients, according to the different pathogenesis of renal edema will be divided into two
categories:
1, nephritis edema: mainly in acute nephritis, or part of acute nephritis and other renal glomerular disease. Edema is mainly due to:
The glomerular filtration rate was decreased, and the kidney ruled out water and sodium decreased and edema occurred;
II ball tube imbalance: glomerular acute inflammation, glomerular filtration rate decreased significantly, but the renal tubular
reabsorption is relatively good, between the ball and tube is out of balance, sodium and water in renal tubular reabsorption
increased relative swelling Erzhi.
The increased capillary hydrostatic pressure, the capillary excess fluid moves to interstitial edema;
The acute nephritis, some patients due to increased blood volume, cause congestive, aggravation of water and sodium retention.
2, nephrotic edema: usually occurs in primary glomerular nephropathy and other causes of nephrotic syndrome. The mechanism of edema
is mainly:
The plasma colloid permeability pressure reduce: nephrotic proteinuria caused by hypoproteinemia, induced plasma colloid osmotic
pressure is reduced, so as to increase the capillary fluid filtration, recovered from interstitial fluids was significantly reduced,
and ultimately the formation of edema.
II decreased effective circulating volume: Extravasation of plasma to reduce the effective blood volume, stimulate intravascular
volume receptors, activation of the renin angiotensin hormone aldosterone system, increased secretion of antidiuretic hormone,
natriuretic hormone is secreted decrease, renal tubular reabsorption of sodium increased, further increase the heavy water, sodium
retention, causing edema. La
IgA nephropathy patients why there is edema, IgA nephropathy with hematuria as the main clinical manifestations and identification
indicators, proteinuria is the secondary identification index of IgA nephropathy. However once the body appear albuminuria, then the
body of water cannot well inhalation to the blood vessel, there will be water infiltration to the organization, at this time,
patients will appear facial swelling or edema in lower extremities, mainly in the swelling of the face and lower extremity edema as
the main. For patients who have been diagnosed with IgA nephropathy, edema is a manifestation of the decline in glomerular and
tubular function.
Through introduction of the content, you should now be clear, experts here suggest the majority of patients with friends, treat
diseases must be timely diagnosis and timely treatment, can not be blind to the effect, lest illness of incur loss through delay,
make the condition worse, bring more serious harm to the patient. In addition, if there are other questions, contact the experts to
consult.
