Filling without feet and renal sodium retention and edema is the primary mechanism resulting capacity regulating hormone also plays a certain effect. In different patients, filling not foot the efficacy and renal sodium retention plays can be different. Colloid osmotic pressure gradient across the capillary, (ie, the difference between plasma colloid osmotic pressure in the colloid osmotic pressure of the cell gap) maintain fluid balance in the cells of intravascular fluid clearance.
In recent years, the survey showed that only a portion of patients with nephrotic edema volume is fewer, the vast majority is to increase the normal plasma renin, angiotensin, aldosterone levels are not elevated or the patient, and blood pressure the presence of high, instead of the display to increase the blood volume decreases. Severe renal comprehensive effects section, gradually reduce the patient's serum albumin concentration resulted into the intercellular spaces colloid osmotic pressure. For MCD patient observation showed hypoalbuminemia very big impact for the occurrence of edema relatively small number of patients discharged severe edema.
In short, comprehensive renal renal sodium retention mechanisms remain a lot, but the exact mechanism needs further deep investigation.
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