Anemia is a common complication of kidney disease. Healthy kidneys can
secrete a horme known as erythropoietin which can stimulate the production of
red blood cells. However, in kidney disease, the diseased kidneys fail to
produce erythropoietin, thus resulting in anemia. With anemia, patients may
suffer from fatigue, weakness, headache and dizziness, etc. Well then, what is
the treatment for renal anemia?
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Patients can take some iron tablets. Iron tablets can provide some raw
material for producing red blood cells. It can relieve anemia to some extent.
However, iron supplement alone is not enough to treat anemia effectively at
all.
The transition from epoetin alfa to darbepoetin alfa therapy is usually
uncomplicated. The approximate conversion is 200 IU of epoetin alfa to 1 mcg of
darbepoetin alfa.In a single--center study, 401 patients with anemia and CKD
were converted from epoetin alfa to once-monthly darbepoetin alfa, with the
intent of increasing the percentage of patients who maintained a stable
hemoglobin level. Initially, patients were converted using the ratio of 1 mcg of
darbepoetin to 200 IU of epoetin. New patients were administered darbepoetin 60
mcg every 2 weeks. Patients with stable hemoglobin ≥ 11.0 were extended to
monthly injections of darbepoetin alfa, with the appropriate dose adjustment.
The proportion of patients who were successfully treated after the conversion
more than doubled with the monthly dose of darbepoetin alfa.
Blood tests should be performed to measure the level of iron in the blood,
and also two vitamins important in the production of red blood cells (vitamin
B12 and folic acid). If there is a deficiency of any of these, supplements can
be given.
Infections may also cause anaemia; this may be temporary if the
infection resolves, but some infections which do not go away rapidly may need
further treatment (for example recurrent urine infections, or infections around
a dialysis catheter). It is also important to detect any blood loss from the
bowel, and any indigestion should be reported to the doctor, as well as any
change in the stools, either with blood being seen, or blackening of the stool
(which can be caused by blood from the stomach, which turns black as it passes
through the bowel).
Immediate treatment of anaemia requires blood transfusions. Adding red blood
cells to the body’s low stocks gives a better oxygen-carrying capacity and hence
improves the anaemia. However the disadvantages of transfusion limit its
usefulness. Usually, patients with renal anemia are suggested to inject EPO. Of
course, there are also many traditonal Chinese treatments can treat renal anemia
effectively. If you want to know more, you can contact with us.